Serpent's Fang

Stats

Values as the League of Legends Wiki's item data lists them, for every mode; the data doesn't state their units.

Effects

• Shield Reaver (unique): Dealing damage to an enemy champion inflicts them with venom for 3 seconds, reducing any shield they gain within the duration by 50%, and if the target was not already afflicted by the venom, reducing all of their active shields by the same amount.³

Arena changes

• Lethality changed to 19.
• Shield reduction for ranged champions changed to 40%.⁴

• Against a large initial shield, a mage that can poke easily can reapply Serpent's Fang's effect after it expires to reduce the shield again. This may be less effective against shields that refresh themselves.⁵
• On an AP champion, Liandry's Torment can pair with Serpent's Fang because its burn can keep applying the venom after the target runs away.⁶

• Attacks during the venom duration do not refresh it or reduce the shield again. Applying venom after it expires can reduce the shield again, even if it was reduced before.⁷⁸
• Shield reduction from Serpent's Fang can trigger omnivamp; the initial shield reduction can trigger healing.⁹¹⁰
• Serpent's Fang halves the shield reduction effect against true damage.¹¹
• Serpent's Fang's effect triggers on damage, not only on physical damage or basic attacks.¹²³

Earlier formats

• Serpent's Fang reduced shields but did not deal damage.¹³¹⁴ 8x2 duos
• Against Karma's shield, Serpent's Fang was an option.¹⁵ 8x2 duos