Glass Cannon

Per level³

• Red Kayn can use a full Glass Cannon build with omnivamp or other sustain to survive extended fights against tank or healing-heavy teams.⁴
• Glass Cannon is an option against champions that stack resistances.⁵

Glass Cannon's pre-mitigation true damage is especially strong on melee champions and decently strong on ranged champions.⁶

• Glass Cannon can let Vladimir one-shot opponents.⁷

Attacking the target dummy can sometimes trigger Glass Cannon damage.⁸⁹

Spell damage works with Glass Cannon, while proc damage does not.¹⁰

With Miss Fortune's Skilled Sniper, the Glass Cannon refund can count as a normal ability rather than damage over time and instantly reset the cooldown; whether Infernal Conduit is required is uncertain.¹¹

Killing the large flower in the middle of the map can remove the health reduction; it can return when the champion dies or when another effect that modifies the allowed maximum-health percentage is picked or upgraded.¹²

K'Sante's health interaction with Glass Cannon appears multiplicative, while the health regained after leaving his R is additive.¹³

Shen's Q interaction was caused by Reverb, even though Glass Cannon was also present.¹⁴