Mystic Punch

• Try Rengar with Ethereal Weapon and Mystic Punch for repeated W casts and healing.³
• Rammus can use Reverberation, Darksteel Talons, Shrink Engine, Mystic Punch, and Ethereal Weapon for a Q with no cooldown; Muramana, Blade of the Ruined King, and Seraph's Embrace were also part of the build.⁴
• Fiora can use Mystic Punch to cast Q and E repeatedly; lifesteal was also used.⁵
• Rengar can use Mystic Punch with Ethereal Weapon and Firebrand or Holy Fire for W spam, healing, and shielding.⁶
• Moonflair Spellblade or Mystic Punch can support nonstop ability spam on Ezreal, though using either can make him harder to play.⁷
• Mystic Punch with Reverberation and Master of Duality is a combination for Transcendence.⁸
• Mystic Punch can let Urgot repeatedly cast E with Reverberation.⁹
• Mystic Punch and Reverberation can repeatedly stun Briar; the combination also works on champions with crowd control in their kits, including Zac, Volibear, Gragas, and Blitzcrank.¹⁰¹¹

• Moonflair Spellblade no longer reduces cooldowns for dash or blink abilities; Mystic Punch is an option for those abilities.¹²
• Combo Break works on knock-ups; how it counts crowd control may explain why it can appear not to trigger.¹³
• Typhoon applies Mystic Punch, but does not work on the same target and deals less damage than level 1.¹⁴
• With Reverberation, Rammus's Q can repeatedly apply its on-hit effects and reduce cooldowns.¹⁵
• Jax's E prevents Ethereal Weapon from triggering during its active period, stopping the Varus mark and cooldown reset loop.¹⁶
• With Lightning Rod and Hexbolt Companion, Hexbolt autocasts and applies the user's on-hit effects; with Mystic Punch and high haste, this can allow repeated ultimate casts.¹⁷
• Reverberation applies Volibear's Q, but does not apply Moonflair Spellblade or Mystic Punch.¹⁸
• Dual Wield triggers Mystic Punch twice.¹⁹
• Mystic Punch and Reverberation on Quinn can repeatedly cast E; Mirage Blade or Moonflair Spellblade can also work in place of Mystic Punch.²⁰
• Vi's Q has a minimum cooldown, so it cannot be spammed like Gragas's E or Briar's and Volibear's Q with Mystic Punch.²¹
• Reverberation and Mystic Punch can keep Alistar's crowd control going for 10 seconds straight.²²
• With Mystic Punch, Dusk and Dawn, Ionian Boots, and Cosmic Drive, Volibear can get W back instantly and cast it repeatedly.²³

Earlier formats

• Mystic Punch with Moonflair Spellblade and Mirage Blade appeared alongside Yi's Q cooldown.²⁵ 8x2 duos
• Bel'Veth's Q could refund all of W and E's remaining cooldowns when she had Mystic Punch.²⁶²⁷²⁸ 8x2 duos